RF3 A Novel Synergistic Antioxidant Blend for Environmental Stress Protection and Inflammaging Prevention:
“This invention marks a paradigm shift in the way we think of antioxidants. This complex adds a new level of security for our customers and delivers on our Founders’ mission of giving all people the best skin of their lives by considering intracellular as well as extracellular reactive oxygen species and explicitly searching for synergistic interactions,” said Dr Tim Falla, Rodan + Fields Chief Scientific Officer.
The complex was created by scientists at the Rodan + Fields Berkeley Innovation Center by systematically refining permutations of ingredients in search of synergistic combinations.
The in-house team demonstrated that one specific permutation, a combination of three different molecules, each targeting different biological mechanisms associated with mitigating the effects of reactive oxygen species, provided additional downstream benefits by mitigating biomarkers inflammaging (inflammation-induced ageing), photoaging, and hyperpigmentation caused by environmental ozone.
The findings support the notion that a multi-mechanistic antioxidant complex can synergistically alleviate environmentally-induced skin damage and provide superior safety when used in skin care formulations.